Mia Thermopolis’ transformation scene from the Princess Diaries (2001) has been etched into every Zillennial’s brain. And Rue’s glitter tears in Euphoria (2019) inspired numerous recreations on Instagram. It’s clear that makeup is inextricably linked to TV and cinema – used to build character, mark change, and even convey emotions without words. In fact, even a simple painted pout has the power to do all of this, and more. Wondering how? Take a look at our lineup of the most memorable on-screen moments where the lipstick brought major main character energy.